Recent Publications
Cell-wall mediated growth and morphing in fungi
Hyphal tip growth enables filamentous fungi to explore their environment, establish colonies, reproduce, and, in some cases, infect host organisms. This mode of growth is characterized by its remarkable morphogenesis including rapid elongation, directional tip turning, branching, and localized bulging. These dynamic shape changes are all driven by the expansion of a mechanically robust cell wall, which is synthesized and secreted from exocytic vesicles.
Using the sporangiophore of the Phycomyces blakesleeanus as a model system, we aim to understand how cell wall secretion, remodeling, and mechanical deformation are spatially and temporally coordinated to enable various morphogenetic outcomes including its helicoidal growth, phototropic, gravitropic and avoidance response.
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Related publications
A statistical model of expansive growth in plant and fungal cells: the case of phycomyces
SL Sridhar, JKE Ortega, FJ Vernerey
Biophysical journal 115 (12), 2428-2442
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A morpho-viscoelasticity theory for growth in proliferating aggregates
P Bandil, FJ Vernerey
Biomechanics and Modeling in Mechanobiology 23 (6), 2155-2176
Catch bond kinetics are instrumental to cohesion of fire ant rafts under load
RJ Wagner, SC Lamont, ZT White, FJ Vernerey
Proceedings of the National Academy of Sciences 121 (17), e2314772121
Self-organization in solids aggregations of active agents
We study networks of active agents, such as cells, bacteria, or insects, that collectively behave as evolving macroscopic solids. Our central aim is to uncover the fundamental communication rules that govern interactions between agents and to understand how these rules give rise to emergent collective behavior, decision-making, and coordinated motion. In particular, we investigate how dense cellular or agent-based networks reorganize, deform, and adapt in response to internal or external cues, with a focus on how individual and collective behaviors guide growth and morphogenesis. These multiscale dynamics are essential to bioengineering applications, where understanding how organoids and tissues self-organize, differentiate, and adapt is key to advancing regenerative medicine and developmental biology. Our group currently focuses on two model systems that, despite their biological differences, share strikingly similar collective dynamics:
(1) Networks of endothelial cells, which drive local morphogenetic events, such as angiogenesis, by actively forming and reorganizing defects in their collective structure, illustrating how tissue-level functions emerge from cellular rearrangements
(2) Aggregations of fire ants, which form dynamic structures like rafts, towers, and bridges that adapt rapidly to environmental changes—achieving complex reconfigurations without centralized control. These systems offer complementary perspectives on how decentralized agents can collectively construct, remodel, and move as living, active materials.
Damage and Fracture of complex polymer networks
Polymers are made up of long, flexible molecular chains intricately connected through a variety of bonds, some permanent and robust, others dynamic and reversible. These bonds weave together to form complex networks with diverse chain lengths, physical properties, and topological architectures. Far from being passive materials, these networks exhibit emergent mechanical behaviors that are highly sensitive to how they are built. Our research explores how the design of polymer networks governs their ability to withstand mechanical stress, resist damage, and avoid catastrophic failure. A central theme of our work is resilience: how do networks hold together, redistribute stress, and adapt under extreme conditions? We are currently investigating three key phenomena.
(1) The sudden formation and evolution of microscopic voids (cavitation) within a polymer network that is subjected to large tensile stresses or negative pressures, particularly relevant in adhesives and soft materials.
(2) The interplay between dynamic and permanent bonds, focusing on how their cooperative behavior can suppress fracture propagation and extend the lifetime of the material.
(3) Plastic flow and damage redistribution in networks with anisotropic or irregular architectures (such as seen in liquid crystal elastomers or bio-polymers), aiming to understand how structural complexity and directionality influence mechanical response.
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Related publications
Generalized continuum theory for nematic elastomers: Non-affine motion and characteristic behavior
SC Lamont, FJ Vernerey
Journal of the Mechanics and Physics of Solids 190, 105718
Nonaffine motion and network reorganization in entangled polymer networks
S Assadi, SC Lamont, N Hansoge, Z Liu, V Crespo-Cuevas, F Salmon, F.J Vernerey
Soft Matter 21 (11), 2096-2113
Cohesive instability in elastomers: insights from a crosslinked Van der Waals fluid model
SC Lamont, N Bouklas, FJ Vernerey
International Journal of Fracture 249 (1), 20